Not of this world

[Yevon]

Let's say an opponent cast a blanket spell like, Damnation. And you have a couple of creatures out in play. Can you select one of them to save with Not of this world?

[Wally]

Let's say an opponent cast a blanket spell like, {Damnation}. And you have a couple of creatures out in play. Can you select one of them to save with {Not of this world}?

Nope, most board wipes (not unlike damnation) don't target. Not of this world requires the spell to have a target.

[Mr_Fahrenheit]

No because damnation doesn't target any of your creatures. It just damns them all!

[FustyDavorite]

 {Damnation} and other spells of that nature do not target, and therefore cannot be countered by  {Not of This World}.

[Kaworu, the Fifth Child]

Also, of ot doesn't explicitly say "target" it doesn't target.