No damage

[Destore117]

 {Personal Sanctuary}
Vs
{Havoc Festival}
Would personal sanctuary negate its effect or is damage different than life loss?

[Anoobass]

As you suspect, damage is different from life loss and it will not work, good try though.

[Destore117]

Is there a card that specifically blocks loss of life (aside from not losing the game from having 0 life)

[MementoMori]

 {Platinum Emperion}