Infinite lock

[BoyMac]

{Tamiyo} + OmniScience (Link for M13 card) + any {counterspell}
Have tamiyo's ultimate go off and always have a 0 cost counter. Even if your counter gets countered, when it resolves it goes back to your hand and you put it right back on the stack .

[Thorn]

Nice!!!!

[DevilGin]

{gut shot}
{tome scour}

[BlackJester]

{Demolish} if you really want to be a douche. 

[Coffee Vampire]

I thought omnisience was only permenants.

[scarsabrex]

nope any spells you cast

[Coffee Vampire]

Wow that's fantastic