{Sadistic Hypnotist} + {Nath of the Gilt-Leaf}
Love this combo.
I know it's so beautiful, all you need is one creature you don't care about to start it off and if they have no responses then their hand is gone.
Isn't there a card that mills if the opponent has to discard? Would be fun in that combo :)
Not that I know of, but we have multiple activations of {Duskmantle Guildmage}!
Or a decked out {Bloodchief Ascension}.
And Bloodchief isn't hard for a Nath EDH deck to get online, lol.
It isn't hard at all. Throw in a blood artist and you'll have that ascension online in no time.
Not edh, but there is {megrim} for the discard part
Megrim works great as well, and why not both? They'd lose 5 life each go around until the ascension started working then they'd lose 9 life each time. That's from sacrificing just one creature.