{Gladecover Scout} or any creature with hexproof + {Indestructibility} + any enchantment that boosts like {Dark Favor}.
Too bad you can still target the enchantments for removal.
{Fountain Watch}, {Sterling Grove}, {Greater Auramancy} can solve that little problem.
It feels good when an opponent has indestructible creatures and you have infect. Or when they have hexproof and you make them sac creatures. There's always a way around!