I played neverwinter nights on PC and I loved the monk class. You get him to level 20 and he gets a 1-20 die. Plus his counter attacks are insane......add a forever haste item on him and he turns into the Tasmanian-fists-of-fury.
I am assuming you are talking about the actual D&D game but I had to get that comment in there 😉
Barbarian-Fighter tank or Cleric are my favs. But it's been quite a while. Last run was a Cleric-Sorcerer in the Eberron setting. Healing both flesh and droids
I once played as a genius half elf half gnome that was a paraplegic and my friend was a giant barbarian with downsyndrom. I would ride him everywhere and he would always pee on everything.